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Network of Cancer Genes & Healthy Drivers
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Retrieve genes that share similar properties
Screenings
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Known Cancer Genes
Futreal
Nature
2004
(556 genes)
Saito
Nature
2020
(96 genes)
Vogelstein
Science
2013
(125 genes)
Pan-cancer studies
Bailey
Cell
2018
(Pan-cancer adult, 299 genes)
Grobner
Nature
2018
(Pan-cancer paediatric, 77 genes)
Hornshoj
npj Genomic Medicine
2018
(Pan-cancer adult, 162 genes)
Hornshoj
npj Genomic Medicine
2018
(Pan-cancer adult, 46 genes)
Juul
eLife
2017
(Pan-cancer adult, 255 genes)
Kandoth
Nature
2013
(Pan-cancer adult, 127 genes)
Lanzos
Scientific Reports
2017
(Pan-cancer adult, 24 genes)
Lanzos
Scientific Reports
2017
(Pan-cancer adult, 15 genes)
Lawrence
Nature
2014
(Pan-cancer adult, 261 genes)
Leiserson
Nature Genetics
2014
(Pan-cancer adult, 147 genes)
Ma
Nature
2018
(Pan-cancer paediatric, 142 genes)
Mularoni
Genome Biology
2016
(Pan-cancer adult, 592 genes)
Mularoni
Genome Biology
2016
(Pan-cancer adult, 222 genes)
Rheinbay
Nature
2020
(Pan-cancer adult, 79 genes)
Rheinbay
Nature
2020
(Pan-cancer adult, 35 genes)
Seiler
Cell Reports
2018
(Pan-cancer adult, 119 genes)
Shuai
Nature Communications
2020
(Pan-cancer adult, 51 genes)
Zhu
Molecular Cell
2020
(Pan-cancer adult, 34 genes)
Gene panel screenings
Barretina
Nature Genetics
2010
(Soft tissue sarcoma, 21 genes)
Beltran
EuropeanUrology
2013
(Prostate cancer, 11 genes)
CancerGenomeAtlas
Nature
2008
(Glioblastoma, 8 genes)
CancerGenomeAtlas
Cancer Cell
2010
(Glioblastoma, 9 genes)
Corre
Leukemia
2018
(Multiple myeloma, 5 genes)
Dalgliesh
Nature
2010
(Clear cell renal cancer, 5 genes)
Ding
Nature
2008
(Lung adenocarcinoma, 26 genes)
Dolnik
Blood
2012
(Acute myeloid leukemia, 16 genes)
Faisal
Clinical Cancer Research
2020
(Prostate cancer, 3 genes)
Jour
HumanPathology
2014
(Soft tissue sarcoma, 8 genes)
Kan
Nature
2010
(Breast cancer, 19 genes)
Kan
Nature
2010
(Lung cancer (all histologies), 47 genes)
Kan
Nature
2010
(Ovarian cancer, 9 genes)
Kan
Nature
2010
(Pancreatic ductal adenocarcinoma, 2 genes)
Kan
Nature
2010
(Prostate cancer, 3 genes)
Lac
Journal of Human Reproduction
2018
(Endometriotic endometrium, 4 genes)
Lac
The Journal of Pathology
2019
(Normal endometrium, 6 genes)
Lipson
Nature Medicine
2012
(Colorectal adenocarcinoma, 12 genes)
Lipson
Nature Medicine
2012
(Non-small cell lung cancer, 10 genes)
Martincorena
Science
2015
(Normal eyelid epidermis, 6 genes)
Martincorena
Science
2018
(Normal oesophageal epithelium, 14 genes)
Pereira
Nature Communications
2016
(Breast cancer, 40 genes)
Piscuoglio
Clinical Cancer Research
2016
(Male breast cancer, 4 genes)
Rampias
Nature Medicine
2014
(Bladder cancer, 5 genes)
Shain
Nature Genetics
2019
(Uveal melanoma, 14 genes)
Solomon
Nature Genetics
2013
(Bladder cancer, 1 gene)
Tang
Nature
2020
(Normal melanocytes, 11 genes)
Weisman
Modern Pathology
2016
(Triple negative breast cancer, 75 genes)
WES and targeted deep resequencing
Chow
Scientific Reports
2017
(Nasopharyngeal carcinoma, 28 genes)
Ibanez
PLOS One
2016
(Acute promyelocytic leukemia, 8 genes)
Lim
AJHG
2016
(Vascular cancer, 1 gene)
Ogura
Genes Chromosomes and Cancer
2017
(Bone giant cell tumour, 1 gene)
TCGA
Cancer Cell
2017
(Pancreatic ductal adenocarcinoma, 14 genes)
Zheng
PNAS
2016
(Nasopharyngeal carcinoma, 2 genes)
WES and gene panel sequencing
Anglesio
NEJM
2017
(Endometriotic endometrium, 4 genes)
Bonilla
Nature
2016
(Skin basal cell carcinoma, 25 genes)
Brunner
Nature
2019
(Normal hepatocytes and cirrhotic hepatocytes, 2 genes)
Gopal
Cancer Cell
2018
(Hurthle cell carcinoma, 1 gene)
Hillman
Nature Communications
2018
(Granulosa tumours of the ovary, 2 genes)
Jiang
Nature Genetics
2015
(Natural killer/T cell lymphoma, 26 genes)
Kovac
Nature Communications
2015
(Osteosarcoma, 14 genes)
Kunstman
Human Molecular Genetics
2015
(Anaplastic thyroid carcinoma, 33 genes)
Li
Scientific Reports
2015
(Lung squamous cell carcinoma, 20 genes)
Madan
Leukemia
2016
(Acute promyelocytic leukemia, 28 genes)
Mareschal
The Journal of Investigative Dermatology
2017
(Cutaneous DLBCL, 24 genes)
Pandya
JCI Insight
2017
(Parathyroid carcinoma, 11 genes)
Sausen
Nature Communications
2015
(Pancreatic ductal adenocarcinoma, 9 genes)
Siraj
AJHG
2016
(Papillary thyroid cancer, 24 genes)
Stieglitz
Nature Genetics
2015
(Juvenile myelomonocytic leukemia, 16 genes)
Suda
Cell Reports
2018
(Normal endometrium and endometriotic endometrium, 14 genes)
Tan
Nature Genetics
2015
(Breast fibroepithelial tumours, 20 genes)
Ungewickell
Nature Genetics
2015
(Cutaneous T cell lymphoma, 17 genes)
Viel
EBioMedicine
2017
(Colorectal adenocarcinoma, 39 genes)
Xia
Molecular Cancer Therapeutics
2015
(Melanoma, 12 genes)
Yachida
Cancer Cell
2016
(Ampullary adenocarcinoma, 24 genes)
Yasumoto
Cancer Medicine
2017
(Gastric adenocarcinoma, 2 genes)
Yokoyama
Nature
2019
(Normal oesophageal epithelium, 10 genes)
Zheng
Cancer Cell
2016
(Adrenocortical carcinoma, 5 genes)
Zhu
Cell
2019
(Non-dysplastic hepatocytes from diseased liver, 26 genes)
WGS
Anderrson
Nature Genetics
2015
(Acute lymphocytic leukemia, 25 genes)
Bailey
Nature
2016
(Pancreatic cancer (all histologies), 41 genes)
Bass
Nature Genetics
2011
(Colorectal adenocarcinoma, 3 genes)
Behjati
Nature Genetics
2013
(Chondroblastoma, 2 genes)
Berger
Nature
2012
(Melanoma, 11 genes)
Chang
Nature Communications
2017
(Esophageal squamous carcinoma, 20 genes)
Cornish
Blood Advances
2019
(Dlblc, follicular lymphoma, 96 genes)
Decker
AJHG
2016
(Prostate cancer, 7 genes)
Ding
Nature
2012
(Acute myeloid leukemia, 5 genes)
Eleveld
Nature Genetics
2015
(Neuroblastoma, 7 genes)
Fels Elliott
PLOSGenetics
2017
(Esophageal adenocarcinoma, 10 genes)
Fujimoto
Nature
2012
(Hepatocellular carcinoma, 23 genes)
Fujimoto
Nature Genetics
2016
(Hepatocellular carcinoma, cholangiocarcinoma, 35 genes)
Fujimoto
Nature Genetics
2016
(Hepatocellular carcinoma, cholangiocarcinoma, 27 genes)
George
Nature
2015
(Small cell lung cancer, 16 genes)
Govindan
Cell
2012
(Non-small cell lung cancer, 9 genes)
Graubert
Nature Genetics
2011
(Myelodysplasia, 1 gene)
Gunawardana
Nature Genetics
2014
(Mediastinal B-cell lymphoma, 2 genes)
Hayward
Nature
2017
(Melanoma, 12 genes)
Hayward
Nature
2017
(Melanoma, 33 genes)
Jones
Nature Genetics
2013
(Astrocytoma, 4 genes)
Jusakul
Cancer Discovery
2017
(Cholangiocarcinoma, 1 gene)
Kiel
JEM
2012
(Splenic marginal zone lymphoma, 1 gene)
Ley
Nature
2008
(Acute myeloid leukemia, 10 genes)
Lopez
Nature Communications
2019
(Burkitt lymphoma, 18 genes)
Mao
Oncotarget
2017
(Hepatocellular carcinoma, 9 genes)
Mardis
NEJM
2009
(Acute myeloid leukemia, 10 genes)
Mehine
NEJM
2013
(Leiomyoma, 2 genes)
Moore
Nature
2020
(Normal endometrium, 12 genes)
Nagata
Blood
2016
(T-cell leukemia/lymphoma, 2 genes)
Nik-Zainal
Cell
2012
(Breast cancer, 8 genes)
Nik-Zainal
Nature
2016
(Breast cancer, 7 genes)
Nik-Zainal
Nature
2016
(Breast cancer, 92 genes)
Nord
Nature Genetics
2014
(Chondromyxoid fibroma, 1 gene)
Olafsson
Cell
2020
(Colonic epithelial crypts from ibd patients, 4 genes)
Panea
Blood
2019
(Burkitt lymphoma, 72 genes)
Panea
Blood
2019
(Burkitt lymphoma, 57 genes)
Patch
Nature
2015
(Ovarian serous carcinoma, 7 genes)
Pena-Llopis
Nature Genetics
2012
(Clear cell renal cancer, 3 genes)
Puente
Nature
2011
(Chronic lymphocytic leukemia, 4 genes)
Robinson
Nature
2012
(Medulloblastoma, 14 genes)
Secrier
Nature Genetics
2016
(Esophageal adenocarcinoma, 7 genes)
Sweeney
Nature Genetics
2014
(Ameloblastoma, 4 genes)
TCGA
Nature
2017
(Cervical cancer (all histologies), 14 genes)
Tirode
Cancer Discovery
2014
(Ewing sarcoma, 4 genes)
Waddell
Nature
2015
(Pancreatic ductal adenocarcinoma, 6 genes)
Wang
Nature Genetics
2014
(Gastric adenocarcinoma, 19 genes)
Weaver
Nature Genetics
2014
(Esophageal adenocarcinoma, 15 genes)
Welch
Cell
2012
(Acute myeloid leukemia, 23 genes)
Wu
Nature Communications
2019
(Bladder cancer, 11 genes)
Wu
Nature Communications
2019
(Bladder cancer, 18 genes)
Yates
Nature Medicine
2015
(Breast cancer, 45 genes)
Yoshida
Nature
2020
(Normal bronchial epithelium, 7 genes)
Zhang
Nature
2012
(Acute lymphoblastic leukemia, 21 genes)
WGS and WES
Buczkowicz
Nature Genetics
2014
(Diffuse intrinsic pontine glioma, 5 genes)
CancerGenomeAtlas
NEJM
2013
(Acute myeloid leukemia, 23 genes)
Ceccarelli
Cell
2016
(Pan-glioma, 75 genes)
Chapman
Nature
2011
(Multiple myeloma, 10 genes)
Choi
Nature Genetics
2015
(Cutaneous T cell lymphoma, 12 genes)
Dulak
Nature Genetics
2012
(Esophageal adenocarcinoma, 26 genes)
Frankell
Nature Genetics
2019
(Esophageal adenocarcinoma, 18 genes)
Frankell
Nature Genetics
2019
(Esophageal adenocarcinoma, 66 genes)
Holmfeldt
Nature Genetics
2013
(Acute lymphocytic leukemia, 19 genes)
Johannson
Oncotarget
2016
(Melanoma, 7 genes)
Jones
Nature
2012
(Medulloblastoma, 8 genes)
Kovac
Nature Communications
2015
(Papillary renal cell carcinoma, 17 genes)
Li
Nature Communications
2016
(Nasopharyngeal carcinoma, 19 genes)
Maura
Nature Communications
2019
(Multiple myeloma, 61 genes)
Merlevede
Nature Communications
2016
(Chronic myelomonocytic leukemia, 26 genes)
Newell
Nature Communications
2019
(Mucosal melanoma, 1 gene)
Newell
Nature Communications
2019
(Mucosal melanoma, 19 genes)
Okosun
Nature Genetics
2014
(Follicular lymphoma, 28 genes)
Paulsson
Nature Genetics
2015
(Acute lymphoblastic leukemia, 9 genes)
Pinto
Nature Communications
2014
(Adrenocortical carcinoma, 4 genes)
Qin
AJHG
2016
(Esophageal squamous carcinoma, 30 genes)
Richter
Nature Genetics
2012
(Burkitt lymphoma, 7 genes)
Scelo
Nature Communications
2014
(Clear cell renal cancer, 17 genes)
Taylor
Nature Genetics
2014
(Diffuse intrinsic pontine glioma, 8 genes)
TCGA
Cell
2015
(Prostate cancer, 13 genes)
TCGA
Nature
2017
(Esophageal (squamous and adenocarcinoma), 12 genes)
TCGA
Cell
2017
(Soft tissue sarcoma, 3 genes)
Wang
NEJM
2011
(Chronic lymphocytic leukemia, 9 genes)
Wu
Nature Genetics
2014
(Paediatric high-grade glioma, 25 genes)
Zhang
Nature Genetics
2013
(Paediatric low grade glioma, 33 genes)
Zhang
Nature Genetics
2014
(Malignant peripheral nerve sheath tumour, 2 genes)
WGS and gene panel sequencing
Brohl
PLOSGenetics
2014
(Ewing sarcoma, 2 genes)
Lee-Six
Nature
2019
(Normal colorectal epithelium, 6 genes)
Mason
Leukemia
2016
(Chronic myelomonocytic leukemia, 30 genes)
WGS, WES and gene panel sequencing
Behjati
Nature Genetics
2014
(Angiosarcoma, 16 genes)
Bueno
Nature Genetics
2016
(Malignant pleural mesothelioma, 10 genes)
Jusakul
Cancer Discovery
2017
(Cholangiocarcinoma, 32 genes)
Kataoka
Nature Genetics
2015
(T-cell leukemia/lymphoma, 50 genes)
Lawson
Science
2020
(Normal bladder urothelium, 17 genes)
Shain
Nature Genetics
2015
(Desmoplastic melanoma, 24 genes)
WES
Agrawal
Science
2011
(Squamous head and neck cancer, 14 genes)
Agrawal
Cancer Discovery
2012
(Esophageal (squamous and adenocarcinoma), 8 genes)
Al-Hebshi
International Journal of Cancer
2016
(Oral squamous cell carcinoma, 13 genes)
Amin-Mansour
Clinical Cancer Research
2019
(Leiomysarcoma, liposarcoma, 5 genes)
Assie
Nature Genetics
2014
(Adrenocortical carcinoma, 6 genes)
Balbas-Martinez
Nature Genetics
2013
(Bladder cancer, 9 genes)
Banerji
Nature
2012
(Breast cancer, 6 genes)
Barbieri
Nature Genetics
2012
(Prostate cancer, 25 genes)
Berger
Cancer Cell
2018
(Pan-gynecological and breast, 46 genes)
Bettegowda
Science
2011
(Oligodendroglioma, 6 genes)
Biankin
Nature
2012
(Pancreatic ductal adenocarcinoma, 16 genes)
Brastianos
Nature Genetics
2014
(Craniopharyngioma, 2 genes)
Campbell
Nature Genetics
2016
(Lung cancer (all histologies), 52 genes)
CancerGenomeAtlas
Nature
2011
(Ovarian cancer, 9 genes)
CancerGenomeAtlas
Nature
2012
(Breast cancer, 35 genes)
CancerGenomeAtlas
Nature
2012
(Colorectal adenocarcinoma, 32 genes)
CancerGenomeAtlas
Nature
2012
(Lung squamous cell carcinoma, 11 genes)
CancerGenomeAtlas
Cell
2013
(Glioblastoma, 71 genes)
CancerGenomeAtlas
Nature
2013
(Clear cell renal cancer, 19 genes)
CancerGenomeAtlas
Nature
2013
(Endometrial cancer, 48 genes)
CancerGenomeAtlas
Nature
2014
(Bladder cancer, 32 genes)
CancerGenomeAtlas
Cancer Cell
2014
(Chromophobe renal cell carcinoma, 2 genes)
CancerGenomeAtlas
Nature
2014
(Lung adenocarcinoma, 18 genes)
CancerGenomeAtlas
Nature
2014
(Gastric adenocarcinoma, 25 genes)
CancerGenomeAtlas
Cell
2014
(Papillary thyroid cancer, 7 genes)
CancerGenomeAtlas
NEJM
2015
(Low grade glioma, 19 genes)
CancerGenomeAtlas
Nature
2015
(Squamous head and neck cancer, 11 genes)
CancerGenomeAtlas
Cell
2015
(Melanoma, 42 genes)
Cao
Science
2014
(Adrenocortical adenoma, 12 genes)
Chan-on
Nature Genetics
2013
(Cholangiocarcinoma, 12 genes)
Chen
Cell Reports
2016
(Renal cancer (all histologies), 20 genes)
Cherniack
Cancer Cell
2017
(Uterine carcinosarcoma, 14 genes)
Cho
Gastroenterology
2017
(Diffuse gastric adenocarcinoma, 10 genes)
Ciriello
Cell
2015
(Breast cancer, 68 genes)
Clark
Science
2013
(Meningioma, 5 genes)
Crompton
Cancer Discovery
2014
(Ewing sarcoma, 1 gene)
DeKeersmaecker
Nature Genetics
2013
(Acute lymphoblastic leukemia, 15 genes)
Durinck
Nature Genetics
2015
(Non-clear cell renal cancer, 18 genes)
Encinas
Oncotarget
2018
(Breast cancer, 53 genes)
Fabbri
JEM
2011
(Chronic lymphocytic leukemia, 1 gene)
Farshidfar
Cell Reports
2017
(Cholangiocarcinoma, 37 genes)
Feber
Cancer Research
2016
(Penile squamous cancer, 38 genes)
Fishbein
Cancer Cell
2017
(Pheochromocytoma, paraganglioma, 5 genes)
Fontebasso
Nature Genetics
2014
(Astrocytoma, 14 genes)
Francis
Nature
2013
(Neuroendocrine tumour, 1 gene)
Gao
Nature Genetics
2014
(Esophageal squamous carcinoma, 18 genes)
Genovese
NEJM
2014
(Normal blood cells, 4 genes)
Gerlinger
NEJM
2012
(Clear cell renal cancer, 4 genes)
Gerlinger
Nature Genetics
2014
(Clear cell renal cancer, 11 genes)
Giannakis
Nature Genetics
2014
(Colorectal adenocarcinoma, 1 gene)
Giannakis
Cell Reports
2016
(Colorectal adenocarcinoma, 90 genes)
Giannikou
PLOSGenetics
2016
(Renal angiomyolipoma, 2 genes)
Gibson
Nature Genetics
2016
(Endometrial cancer, 49 genes)
Gingras
Cell Reports
2016
(Ampullary adenocarcinoma, 23 genes)
Goh
Nature Genetics
2014
(Adrenocortical adenoma, 1 gene)
Gopal
Cancer Cell
2018
(Hurthle cell carcinoma, 24 genes)
Grasso
Nature
2012
(Prostate cancer, 9 genes)
Greif
Leukemia
2011
(Acute myeloid leukemia, 3 genes)
Gui
Nature Genetics
2011
(Bladder cancer, 21 genes)
Guichard
Nature Genetics
2012
(Hepatocellular carcinoma, 10 genes)
Guo
Nature Genetics
2012
(Clear cell renal cancer, 23 genes)
Guo
Nature Genetics
2013
(Bladder cancer, 37 genes)
Heo
BMC Medical Genetics
2017
(Acute myeloid leukemia, 11 genes)
Hintzsche
British Journal of Haematology
2017
(Mucosal melanoma, 18 genes)
Hmeljak
Cancer Discovery
2018
(Malignant pleural mesothelioma, 5 genes)
Hodis
Cell
2012
(Melanoma, 12 genes)
Huang
Nature Genetics
2012
(Hepatocellular carcinoma, 10 genes)
Huang
Scientific Reports
2016
(Squamous head and neck cancer, 26 genes)
Imielinski
Cell
2012
(Lung adenocarcinoma, 25 genes)
Jaiswal
NEJM
2014
(Normal blood cells, 10 genes)
Jiao
Science
2011
(Pancreatic neuroendocrine tumours, 6 genes)
Jiao
Nature Genetics
2013
(Cholangiocarcinoma, 5 genes)
Johnson
Science
2014
(Low grade glioma, 4 genes)
Jones
Science
2008
(Pancreatic ductal adenocarcinoma, 82 genes)
Jones
Science
2010
(Ovarian clear-cell carcinoma, 4 genes)
Jung
Clinical Cancer Research
2018
(Gastric adenocarcinoma, 55 genes)
Kadara
Annals of Oncology
2017
(Lung adenocarcinoma, 28 genes)
Kakiuchi
Nature Genetics
2014
(Diffuse gastric adenocarcinoma, 1 gene)
Klampfl
NEJM
2013
(Myeloproliferative neoplasm, 1 gene)
Kohsaka
Nature Genetics
2014
(Rhabdomyosarcoma, 1 gene)
Kooi
Scientific Reports
2016
(Retinoblastoma, 3 genes)
Krauthammer
Nature Genetics
2012
(Melanoma, 15 genes)
Krauthammer
Nature Genetics
2015
(Melanoma, 13 genes)
Krysiak
Blood
2017
(Follicular lymphoma, 39 genes)
Landau
Cell
2013
(Chronic lymphocytic leukemia, 20 genes)
Landau
Nature
2015
(Chronic lymphocytic leukemia, 44 genes)
Lasorsa
Oncotarget
2016
(Neuroblastoma, 22 genes)
Le Gallo
Nature Genetics
2012
(Serous endometrial cancer, 9 genes)
Le Gallo
Cancer
2017
(Clear cell endometrial cancer, 7 genes)
Lee
JCI
2012
(Rhabdoid tumour, 2 genes)
Lee
Nature Genetics
2014
(Malignant peripheral nerve sheath tumour, 5 genes)
Lee
Gastric Cancer
2019
(Gastric cancer, 24 genes)
Lefebvre
PLOS Medicine
2016
(Breast cancer, 12 genes)
Li
Nature Genetics
2011
(Hepatocellular carcinoma, 5 genes)
Li
Nature Genetics
2014
(Gallbladder carcinoma, 6 genes)
Lim
Nature Genetics
2014
(Breast fibroadenoma, 1 gene)
Lin
Nature Genetics
2014
(Esophageal squamous carcinoma, 13 genes)
Lin
Nature Genetics
2014
(Nasopharyngeal carcinoma, 27 genes)
Litchfield
Nature Communications
2015
(Testicular germ cell cancer, 12 genes)
Liu
Carcinogenesis
2012
(Non-small cell lung cancer, 11 genes)
Liu
Cancer Cell
2018
(Pan-gastric, 57 genes)
Lohr
PNAS
2011
(Diffuse large B-cell lymphoma, 74 genes)
Love
Nature Genetics
2012
(Burkitt lymphoma, 18 genes)
Lui
Cancer Discovery
2013
(Squamous head and neck cancer, 18 genes)
Lyu
The Journal of Pathology
2017
(Mucosal melanoma, 5 genes)
Mareschal
Genes Chromosomes and Cancer
2015
(Diffuse large B-cell lymphoma, 15 genes)
Morin
Nature
2011
(Non-Hodgkin lymphoma, 30 genes)
Nakamura
Nature Genetics
2015
(Biliary tract cancer, 32 genes)
Nangalia
NEJM
2013
(Myeloproliferative neoplasm, 9 genes)
Nikolaev
Nature Genetics
2011
(Melanoma, 7 genes)
Ojesina
Nature
2013
(Cervical cancer (all histologies), 10 genes)
Ong
Nature Genetics
2012
(Cholangiocarcinoma, 15 genes)
Palomero
Nature Genetics
2014
(Peripheral T-cell lymphoma, 8 genes)
Pan
Human Molecular Genetics
2016
(Papillary thyroid cancer, 3 genes)
Pan
Human Molecular Genetics
2016
(Papillary thyroid cancer, 10 genes)
Papaemmanuil
NEJM
2011
(Myelodysplasia, 1 gene)
Papaemmanuil
Nature Genetics
2014
(Acute lymphoblastic leukemia, 14 genes)
Parsons
Science
2008
(Glioblastoma, 40 genes)
Parsons
Science
2011
(Medulloblastoma, 7 genes)
Pasqualucci
Nature Genetics
2011
(Diffuse large B-cell lymphoma, 56 genes)
Pasqualucci
Nature
2011
(Diffuse large B-cell lymphoma, 2 genes)
Peifer
Nature Genetics
2012
(Small cell lung cancer, 23 genes)
Petrini
Nature Genetics
2014
(Thymic carcinoma, 12 genes)
Piazza
Nature Genetics
2013
(Chronic myeloid leukemia, 2 genes)
Pierson
Gynecologic Oncology
2020
(Endometrioid ovarian cancer, 8 genes)
Pugh
Nature
2012
(Medulloblastoma, 12 genes)
Pugh
Nature Genetics
2013
(Neuroblastoma, 7 genes)
Quesada
Nature Genetics
2012
(Chronic lymphocytic leukemia, 78 genes)
Radovich
Cancer Cell
2018
(Thymic carcinoma, 4 genes)
Ramsay
Nature Genetics
2013
(Chronic lymphocytic leukemia, 1 gene)
Rashid
Nature Communications
2019
(Cylindroma, spiradenocarcinoma, spiradenoma, 4 genes)
Rheinbay
Nature
2017
(Breast cancer, 9 genes)
Robertson
Cell
2017
(Bladder cancer, 58 genes)
Robertson
Cancer Cell
2017
(Melanoma, 9 genes)
Robinson
Nature Genetics
2013
(Breast cancer, 1 gene)
Robinson
Cell
2015
(Prostate cancer, 37 genes)
Rokutan
The Journal of Pathology
2016
(Mucinous gastric cancer, 23 genes)
Rudin
Nature Genetics
2012
(Small cell lung cancer, 22 genes)
Sakata-Yanagimoto
Nature Genetics
2014
(Angioimmunoblastic T-cell lymphoma, 4 genes)
Sausen
Nature Genetics
2012
(Neuroblastoma, 5 genes)
Schramm
Nature Genetics
2015
(Neuroblastoma, 23 genes)
Schulze
Nature Genetics
2015
(Hepatocellular carcinoma, 14 genes)
Schwartzentruber
Nature
2012
(Glioblastoma, 4 genes)
Seshagiri
Nature
2012
(Colorectal adenocarcinoma, 23 genes)
Shen
Cell Reports
2018
(Testicular germ cell cancer, 3 genes)
Stark
Nature Genetics
2012
(Melanoma, 2 genes)
Stephens
Nature
2012
(Breast cancer, 34 genes)
Stransky
Science
2011
(Squamous head and neck cancer, 76 genes)
Tarpey
Nature Genetics
2013
(Chondrosarcoma, 5 genes)
TCGA
NEJM
2015
(Papillary renal cell carcinoma, 11 genes)
TCGA
Cell
2017
(Hepatocellular carcinoma, 28 genes)
Togasaki
Blood Cancer Journal
2017
(Chronic myeloid leukemia, 27 genes)
Totoki
Nature Genetics
2014
(Hepatocellular carcinoma, 29 genes)
Toy
Nature Genetics
2013
(Breast cancer, 1 gene)
Varela
Nature
2011
(Clear cell renal cancer, 1 gene)
Vasudevan
Cell Reports
2018
(Meningioma, 17 genes)
Wang
Nature Genetics
2011
(Gastric adenocarcinoma, 20 genes)
Wang
GenomeResearch
2012
(Pancreatic ductal adenocarcinoma, 56 genes)
Wang
Nature
2014
(Intracranial germ cell, 11 genes)
Wang
Nature Genetics
2016
(Glioblastoma, 13 genes)
Wei
Nature Genetics
2011
(Melanoma, 68 genes)
Weinreb
Nature Genetics
2014
(Salivary gland adenocarcinoma, 1 gene)
Witkiewicz
Nature Communications
2015
(Pancreatic ductal adenocarcinoma, 24 genes)
Witkowski
Nature Genetics
2014
(Ovarian small-cell carcinoma, 1 gene)
Wu
PNAS
2011
(Pancreatic neoplastic cysts, 5 genes)
Wu
Oncotarget
2016
(Bladder cancer, 24 genes)
Xie
Nature Medicine
2014
(Normal blood cells, 9 genes)
Xu
Modern Pathology
2020
(Ocular adnexal sebaceous carcinoma, 5 genes)
Yan
Nature Genetics
2011
(Acute monocytic leukemia, 6 genes)
Yoo
Nature Genetics
2014
(Angioimmunoblastic T-cell lymphoma, 2 genes)
Yoshida
Nature
2011
(Myelodysplasia, 12 genes)
Yuan
Cancer
2016
(Duodenal adenocarcinoma, 10 genes)
Zang
Nature Genetics
2012
(Gastric adenocarcinoma, 28 genes)
Zhang
Nature Genetics
2014
(Glioma, 7 genes)
Zhang
Science
2014
(Lung adenocarcinoma, 10 genes)
Zhao
PNAS
2016
(Uterine carcinosarcoma, 10 genes)
Primary Sites
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Adrenal gland
Bladder
Blood
Bone
Brain
Breast
Cervix
Colorectal
Esophagus
Head and neck
Hepatobiliary
Kidney
Lung
Ovarian
Pancreas
Parathyroid gland
Penis
Peripheral nervous system
Pleura
Prostate
Retina
Skin
Small intestine
Soft tissue
Stomach
Testis
Thymus
Thyroid
Uterus
Uvea
Vascular system
Cancer Types
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Acute lymphoblastic leukemia
Acute lymphocytic leukemia
Acute monocytic leukemia
Acute myeloid leukemia
Acute promyelocytic leukemia
Adrenocortical adenoma
Adrenocortical carcinoma
Ameloblastoma
Ampullary adenocarcinoma
Anaplastic thyroid carcinoma
Angioimmunoblastic T-cell lymphoma
Angiosarcoma
Astrocytoma
Biliary tract cancer
Bladder cancer
Bone giant cell tumour
Breast cancer
Breast fibroadenoma
Breast fibroepithelial tumours
Burkitt lymphoma
Cervical cancer (all histologies)
Cholangiocarcinoma
Chondroblastoma
Chondromyxoid fibroma
Chondrosarcoma
Chromophobe renal cell carcinoma
Chronic lymphocytic leukemia
Chronic myeloid leukemia
Chronic myelomonocytic leukemia
Clear cell endometrial cancer
Clear cell renal cancer
Colonic epithelial crypts from ibd patients
Colorectal adenocarcinoma
Craniopharyngioma
Cutaneous DLBCL
Cutaneous T cell lymphoma
Cylindroma, spiradenocarcinoma, spiradenoma
Desmoplastic melanoma
Diffuse gastric adenocarcinoma
Diffuse intrinsic pontine glioma
Diffuse large B-cell lymphoma
Dlblc, follicular lymphoma
Duodenal adenocarcinoma
Endometrial cancer
Endometrioid ovarian cancer
Endometriotic endometrium
Esophageal (squamous and adenocarcinoma)
Esophageal adenocarcinoma
Esophageal squamous carcinoma
Ewing sarcoma
Follicular lymphoma
Gallbladder carcinoma
Gastric adenocarcinoma
Gastric cancer
Glioblastoma
Glioma
Granulosa tumours of the ovary
Hepatocellular carcinoma
Hepatocellular carcinoma, cholangiocarcinoma
Hurthle cell carcinoma
Intracranial germ cell
Juvenile myelomonocytic leukemia
Leiomyoma
Leiomysarcoma, liposarcoma
Low grade glioma
Lung adenocarcinoma
Lung cancer (all histologies)
Lung squamous cell carcinoma
Male breast cancer
Malignant pleural mesothelioma
Malignant peripheral nerve sheath tumour
Mediastinal B-cell lymphoma
Medulloblastoma
Melanoma
Meningioma
Mucinous gastric cancer
Mucosal melanoma
Multiple myeloma
Myelodysplasia
Myeloproliferative neoplasm
Nasopharyngeal carcinoma
Natural killer/T cell lymphoma
Neuroblastoma
Neuroendocrine tumour
Non-clear cell renal cancer
Non-dysplastic hepatocytes from diseased liver
Non-Hodgkin lymphoma
Non-small cell lung cancer
Normal bladder urothelium
Normal blood cells
Normal bronchial epithelium
Normal colorectal epithelium
Normal endometrium
Normal endometrium and endometriotic endometrium
Normal eyelid epidermis
Normal hepatocytes and cirrhotic hepatocytes
Normal melanocytes
Normal oesophageal epithelium
Ocular adnexal sebaceous carcinoma
Oligodendroglioma
Oral squamous cell carcinoma
Osteosarcoma
Ovarian cancer
Ovarian clear-cell carcinoma
Ovarian serous carcinoma
Ovarian small-cell carcinoma
Paediatric high-grade glioma
Paediatric low grade glioma
Pan-cancer adult
Pan-cancer paediatric
Pan-gastric
Pan-glioma
Pan-gynecological and breast
Pancreatic cancer (all histologies)
Pancreatic ductal adenocarcinoma
Pancreatic neoplastic cysts
Pancreatic neuroendocrine tumours
Papillary renal cell carcinoma
Papillary thyroid cancer
Parathyroid carcinoma
Penile squamous cancer
Peripheral T-cell lymphoma
Pheochromocytoma, paraganglioma
Prostate cancer
Renal angiomyolipoma
Renal cancer (all histologies)
Retinoblastoma
Rhabdoid tumour
Rhabdomyosarcoma
Salivary gland adenocarcinoma
Serous endometrial cancer
Skin basal cell carcinoma
Small cell lung cancer
Soft tissue sarcoma
Splenic marginal zone lymphoma
Squamous head and neck cancer
T-cell leukemia/lymphoma
Testicular germ cell cancer
Thymic carcinoma
Triple negative breast cancer
Uterine carcinosarcoma
Uveal melanoma
Vascular cancer
Gene Function (Reactome)
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Cell cycle
Cell-cell communication
Cellular responses to external stimuli
Chromatin organization
Circadian clock
Developmental biology
Digestion and absorption
DNA repair
Extracellular matrix organization
Gene expression (transcription)
Hemostasis
Immune system
Metabolism
Metabolism of proteins
Metabolism of RNA
Mitophagy
Muscle contraction
Neuronal system
Organelle biogenesis and maintenance
Programmed cell death
Reproduction
Signal transduction
Transport of small molecules
Vesicle-mediated transport
Appearance in Evolution
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Last Universal Common Ancestor
Eukaryotes
Opisthokonts
Metazoans
Vertebrates
Mammals
Primates
Gene Duplication
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Duplicated Genes
Singleton Genes
PPIN
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Hubs
Non-hubs
microRNA-gene Network
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Hubs
Non-hubs
Essentiality
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Essential in at least one cell line
Never essential