Info Results for PTEN



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PTEN
Description: phosphatase and tensin homolog Aliases: 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC11, PTENbeta, TEP1, PTEN
Gene Identifiers mRNA Identifiers Protein Identifiers Protein Architecture Disease Mapping Druggability
Entrez ID: 5728
RefSeq (protein):
SMART: domain composition
COSMIC: cancer mutations
Uniprot ID:
Ensembl Gene ID:
Ensembl protein ID:
OMIM: 601728 Pubmed: literature

Info Cancer Information
This gene is a tumour suppressor gene, significantly mutated in 20 primary sites.

Info Duplicability
This gene has 1 duplicated locus at 60% coverage

Info Orthology
This gene originated with Last Universal Common Ancestor

Info Network Properties
This protein interacts with 240 protein(s) and is part of at least one complex

Info Gene Expression in Normal Tissues
Info Gene Expression in Cancer Cell Lines
Info Protein Expression in Normal Tissues
Info Gene Essentiality
This gene is essential in 8 out of 170 human cell lines

Info Protein Function

Info miRNA-Gene Interactions
This gene interacts with 113 miRNAs